Superinduction of Cytotoxic Interferon-β in Glioma Cells
نویسندگان
چکیده
منابع مشابه
Interferon-α/β enhances temozolomide activity against MGMT-positive glioma stem-like cells.
Glioma is one of the most common primary tumors of the central nervous system in adults. Glioblastoma (GBM) is the most lethal type of glioma, whose 5-year survival is 9.8% at best. Glioma stem-like cells (GSCs) play an important role in recurrence and treatment resistance. MGMT is a DNA repair protein that removes DNA adducts and therefore attenuates treatment efficiency. It has been reported ...
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ژورنال
عنوان ژورنال: Neurologia medico-chirurgica
سال: 1991
ISSN: 0470-8105,1349-8029
DOI: 10.2176/nmc.31.485